There is a thread about this on r/CRISPR.
https://www.reddit.com/r/CRISPR/comments/1bcj6wu/biotech_startup_minicircle_is_engineering_a
The science around this phenotype is not settled. It is based on only one case study which is now being called into question. Databases show similar genetic changes in a small, but significant, part of the population. There are other concerns as well.